Peptide vaccines based on tumor antigens face the challenges of rapid clearance of peptides, low immunogenicity, and immune suppressive tumor microenvironment.However, the traditional solution mainly uses exogenous substances as adjuvants or carriers to enhance innate immune responses, but excessive inflammation can damage adaptive immunity.In the
Childhood hyperactivity, physical aggression and criminality: a 19-year prospective population-based study.
Research shows that children with Attention Deficit/Hyperactivity Disorder are stone holder at elevated risk of criminality.However, several issues still need to be addressed in order to verify whether hyperactivity in itself plays a role in the prediction of criminality.In particular, co-occurrence with other behaviors as well as the internal hete
Attachment, neurobiology, and mentalizing along the psychosis continuum
In this review article, we outline the evidence linking attachment adversity to the psychosis, from the premorbid stages of the disorder to its clinical forms.To better understand the neurobiological mechanisms through which insecure attachment may contribute to psychosis, we identify at least five neurobiological pathways linking attachment to ris
The role of physical activity against chemotherapy-induced peripheral neuropathy: a narrative review
Several studies investigated the side effect of adjuvant cancer treatments, and different types of preventive techniques or treatments have been assessed.Chemotherapy-induced peripheral neuropathy (CIPN) is the most common neurological side effect.Exercise training has been widely studied as an adjuvant therapy to prevent CIPN and improve post-chem
Penerapan Algoritma K-Means untuk Klasterisasi Penduduk Miskin pada Kota Pagar Alam
The purpose of this study was to obtain a poverty data cluster in Pagar Alam City.The data collection of beneficiaries of the Program Keluarga Harapan (PKH) is not correct, the provision of assistance only pays attention to the criteria for poverty in general, so Mens Tshirt there are still many poor people who feel more deserving of PKH assistance